The Biological Responses of Staphylococcus aureus to Cold Plasma Treatment

Staphylococcus aureus is a bacterium that causes various diseases in humans. Cold plasma found to be an alternative eliminate S. aureus. Most studies of cold on mainly focus the physiochemical changes cells. So far, biological responses treatment under different durations have not yet been evaluated. In this study, results showed was effective eliminating At initial exposure (1 min), treated cells gene upregulations stress proteins, antioxidants, nitrosative stress, and transporter but no significant change other processes, such as cell membrane synthesis, DNA repairing, transcription, translation. This indicated actively countered damage from plasma. contrast, during prolonged (3 5 processes related central dogma were affected, including repairing mechanism, addition, majority genes synthesis downregulated, indicating could longer sustain their integrity. conclusion, study elucidated how inactivated series exposures highlighted sequential transcriptomic